These machines are sold as stand-alone manually operated for a dedicated task, or optionally integrated into automation cells. All machines listed here can perform either role. A machine used in a manual application can be upgraded for automation in field, and any machine operating in an automatic cell can be operated manually. This gives the customer the maximum flexibility for their investment, and allows the machine to be used as automation budgets increase, and allows the machine to be used if surrounding automation should fail.

A very popular use of these machines is "one-off" filling with brand new sterile empty vials. The -A model is required, with two Vial Nests. Empty and closed (new) vials (for clinical operations, this is an excellent way to maintain sterility) are loaded into the capping machine right hand Vial Nest. The machine pulls the vial inside where it is opened, the new sterile cap is held inside the machine in the Cap Grippers, and the open vial is returned outside. There the vial is taken away and processed, maybe one, maybe many, various steps. Eventually the vial is returned to the capping machine and loaded into the left hand Vial Nest. On the next machine cycle this filled and finished vial is pulled inside, and the sterile cap, just taken off another new sterile vial (one-off), is capped to six-sigma accuracy to the vial just presented. Caps, as separate entities, never leave the machine.

The use of right hand for empty vials, and left hand for filled vials mitigate cross contamination issues. All traces flow in one direction outbound; never across.

Another "one-off" variation is to process the open vial while it resides in the Vial Nest and immediately pull it back in to be re-capped. The robot, or operator unloads a closed finished vial, loads a closed new vial, and can process the open vial even while it sits in the Vial Nest. Most often the vial is taken away, and then brought back for recapping to the same cap previously removed.

Another popular use of the EP-314-5-A is for manual capping. Most customers buy the -A for future flexibility. Generally, the right hand device is the Vial Nest and the left hand is the Cap Post. The vials usually come from trays, just off an automation platform, and the caps from a bulk hopper. Ergonomics are a very important part of the EP's design. It completely eliminates risk to hands and wrists from the constant twisting motion of applying torque to vials. And, it insures each and every vial is to the same exact torque.